Knowing more about the cause of functional disorders has made a tremendous impact on their treatment. Typically, children with cyclic vomiting syndrome suffer from multiple incapacitating episodes of severe nausea and vomiting, often for days up to a week at a time and recurring every few weeks to months. Dr. Boles has found that adding mitochondrial-directed treatments to traditional drug therapy is highly effective. Those mito-treatments consist of high-doses of the enzyme cofactors co-enzyme Q10, riboflavin and L-carnitine (“mito-cocktail”), as well as frequent feedings and exercise. About a hundred children and young adults have been treated by Dr. Boles, and essentially all of them no longer suffer from vomiting episodes.